PDCD7

Across TCGA cell cohorts, PDCD7 mutation is significantly associated with the mutation status of many other genes, with 1,587 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PDCD7-associated genes across cancer lineages are CCNG2, NUAK2, and ZMYND11. Each is linked with PDCD7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PDCD7-to-partner and partner-to-PDCD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNG2 grouped by PDCD7-low versus PDCD7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD7→partner) and Y-score (partner→PDCD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCNG2 →	+4.329	+4.329	.001	.001	1	3
LARGE_INTESTINE	NUAK2 →	+3.007	+3.584	.008	.008	1	3
LARGE_INTESTINE	ZMYND11 →	+3.744	+4.044	.003	.003	1	2
LARGE_INTESTINE	TRIP6 →	+3.744	+4.044	.003	.003	1	2
LARGE_INTESTINE	KLHL13 →	+2.422	+4.050	.004	.004	1	2
LARGE_INTESTINE	PRSS22 →	+3.744	+4.044	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,587 associations by consensus.

CCNG2 by PDCD7 expression — LARGE_INTESTINE

Explore this box plot interactively →