PDCD6IP

Across TCGA patient cohorts, PDCD6IP mutation is significantly associated with the RNA expression of many other genes, with 1,508 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDCD6IP-associated genes across cancer lineages are MIR4311, TRAJ58, and MIR2355. Each is linked with PDCD6IP in more than 2 cancer types. Because this analysis shows association rather than direction, both PDCD6IP-to-partner and partner-to-PDCD6IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4311 grouped by PDCD6IP-low versus PDCD6IP-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD6IP→partner) and Y-score (partner→PDCD6IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4311 →	+0.303	+5.144	.001	.003	3	3
UCEC	TRAJ58 →	+0.287	+1.772	<.001	.007	3	3
LIHC	MIR2355 →	+0.439	+5.008	<.001	.004	3	2
CESC	SSU72P8 →	+0.473	+5.144	.002	.003	3	2
UCEC	RNA5SP412 →	+0.367	+1.744	.003	.003	3	2
CESC	RPL5P15 →	+0.054	+4.276	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,508 associations by consensus.

MIR4311 by PDCD6IP expression — CESC

Explore this box plot interactively →