PDCD6

Across TCGA patient cohorts, PDCD6 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDCD6-associated genes across cancer lineages are Macrophages, lymphatic Endothelial cells, and mv Endothelial cells. Each is linked with PDCD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDCD6-to-partner and partner-to-PDCD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macrophages grouped by PDCD6-low versus PDCD6-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD6→partner) and Y-score (partner→PDCD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Macrophages →	+0.022	+2.703	.015	.029	3	2
UCEC	lymphatic Endothelial cells →	-0.027	-3.129	.037	.019	3	1
UCEC	mv Endothelial cells →	-0.033	-3.159	.011	.020	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Macrophages by PDCD6 expression — COAD

Explore this box plot interactively →