PDCD5P1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PDCD5P1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PDCD5P1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher PDCD5P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PDCD5P1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and THCA show a favorable association.

MESO, STAD, and LUSC are the cancer types where PDCD5P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESODFSTertileAll0.2420.462<.00172view →
STADOSMedianAll0.6250.744.00557view →
LUSCOSMedianII,III,IV0.4940.271<.00149view →
LIHCDFSQuartileAll0.4550.664.00140view →
KICHDFSQuartileIII,IV0.0471.000.00537view →
BRCADFSMedianIV0.3230.746.00531view →
CHOLDFSTertileAll0.0880.553.00428view →
THCADFSMedianIII,IV0.8640.250.00427view →
KIRPOSMedianAll0.6040.755.00626view →
CESCDFSMedianII,III,IV0.8840.682.00518view →
THYMDFSQuartileIII,IV0.4381.000.01712view →
KIRCDFSTertileIV0.4950.699.01110view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PDCD5P1–MESO (DFS)

Kaplan–Meier survival curve for PDCD5P1 RNA-high vs -low samples in MESO.

Open the MESO breakdown →

Exploration