PDCD5P1

Across TCGA pan-cancer cohorts, PDCD5P1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of PDCD5P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PDCD5P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PDCD5P1 is over-expressed in tumor.

COAD, HNSC, and BLCA are the cancer types where PDCD5P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PDCD5P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.035	<.001	9	view →
HNSC	All	All	+0.251	.001	9	view →
BLCA	Male	All	+0.670	<.001	8	view →
UCEC	All	All	+0.551	.001	6	view →
LUSC	All	II,III,IV	+0.543	<.001	6	view →
KIRC	Female	III,IV	+0.335	.001	6	view →
STAD	All	II,III,IV	+0.320	.015	4	view →
BRCA	All	III,IV	+0.169	.009	4	view →
LIHC	All	All	+0.126	<.001	4	view →
LUAD	All	All	+0.244	.006	3	view →
ESCA	All	II,III,IV	+0.575	.048	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

PDCD5P1–COAD

Open the COAD breakdown →