PDCD2L

Across TCGA cell cohorts, PDCD2L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,095 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PDCD2L-associated GO terms across cancer lineages are rRNA processing, rRNA metabolic process, and Ribosome biogenesis. Each is linked with PDCD2L in more than 16 cancer types. Because this analysis shows association rather than direction, both PDCD2L-to-partner and partner-to-PDCD2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA processing grouped by PDCD2L-low versus PDCD2L-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD2L→partner) and Y-score (partner→PDCD2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	rRNA processing →	+0.115	+0.763	.002	.002	3	17
LUNG_SCLC	rRNA metabolic process →	+0.123	+0.776	<.001	.002	3	17
BONE	Ribosome biogenesis →	+0.127	+1.058	.001	.004	3	17
URINARY_TRACT	Ribosomal small subunit biogenesis →	+0.103	+0.909	.001	.007	3	17
LUNG_SCLC	Nucleolar large rRNA transcription by RNA polymerase I →	+0.125	+0.811	<.001	<.001	3	16
BLOOD_Lymphoma	Ribosome assembly →	+0.081	+0.971	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,095 associations by consensus.

rRNA processing by PDCD2L expression — LUNG_SCLC

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