PDCD1LG2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PDCD1LG2 mutation is significantly associated with the RNA expression of many other genes, with 2,558 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDCD1LG2-associated genes across cancer lineages are LINC02553, MIR4692, and MIR1290. Each is linked with PDCD1LG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PDCD1LG2-to-partner and partner-to-PDCD1LG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD1LG2→partner) and Y-score (partner→PDCD1LG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCALINC02553 →+0.070+6.147<.001.00232
BLCAMIR4692 →+0.495+5.411<.001.00532
LUADMIR1290 →+0.915+5.157<.001.00732
LUADDUSP12P1 →+0.090+5.481.003.00532
UCECRNA5SP419 →+0.900+2.884<.001<.00132
BLCATRAJ61 →+0.762+5.899<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,558 associations by consensus.

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