PDCD10

Across TCGA patient cohorts, PDCD10 mutation is significantly associated with the RNA expression of many other genes, with 721 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PDCD10-associated genes across cancer lineages are RNA5SP412, LINC01072, and LINC02559. Each is linked with PDCD10 in more than 2 cancer types. Because this analysis shows association rather than direction, both PDCD10-to-partner and partner-to-PDCD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by PDCD10-low versus PDCD10-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PDCD10→partner) and Y-score (partner→PDCD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP412 →	+0.343	+7.640	<.001	.009	3	3
HNSC	LINC01072 →	+0.215	+5.241	<.001	.007	3	2
HNSC	LINC02559 →	+1.400	+5.505	<.001	.004	3	2
HNSC	RNA5SP183 →	+0.285	+5.578	<.001	.004	3	2
CESC	MIR450A1 →	+0.460	+4.812	<.001	.006	3	2
CESC	TRAJ57 →	+0.447	+4.539	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 721 associations by consensus.

RNA5SP412 by PDCD10 expression — BLCA

Explore this box plot interactively →