PDC-AS1

Across TCGA patient cohorts, PDC-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,875 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDC-AS1-associated proteins across cancer lineages are POGK, VEZF1, and MYO1E. Each is linked with PDC-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PDC-AS1-to-partner and partner-to-PDC-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDC-AS1 versus POGK in UCEC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDC-AS1→partner) and Y-score (partner→PDC-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POGK →	+0.342	+0.891	<.001	<.001	3	4
GBM	VEZF1 →	+0.477	+0.600	<.001	<.001	3	3
GBM	MYO1E →	-0.349	-0.523	<.001	<.001	3	3
LUAD	NUCB1_T148 →	-0.419	-0.357	<.001	.001	3	3
BRCA	NUCKS1 →	+0.452	+0.306	.004	.005	3	3
HNSC	PARP1 →	+0.339	+0.465	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,875 associations by consensus.

PDC-AS1 vs POGK — UCEC

Explore this scatter interactively →