PCYT1A

Across TCGA patient cohorts, PCYT1A RNA expression is significantly associated with the protein abundance of many other proteins, with 13,703 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCYT1A-associated proteins across cancer lineages are PAK2, ACAP2, and ABCF3. Each is linked with PCYT1A in more than 8 cancer types. Because this analysis shows association rather than direction, both PCYT1A-to-partner and partner-to-PCYT1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCYT1A versus PAK2 in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYT1A→partner) and Y-score (partner→PCYT1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PAK2 →	+0.253	+0.685	<.001	<.001	3	9
LSCC	ACAP2 →	+0.473	+0.932	<.001	<.001	3	7
LSCC	ABCF3 →	+0.293	+0.748	<.001	<.001	3	6
LUAD	FXR1 →	+0.393	+0.420	<.001	<.001	3	6
LSCC	POLR2H →	+0.456	+0.892	<.001	<.001	3	5
BRCA	NUDT16 →	+0.246	+0.285	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,703 associations by consensus.

PCYT1A vs PAK2 — HNSC

Explore this scatter interactively →