PCYT1A

Across TCGA cell cohorts, PCYT1A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,477 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PCYT1A-associated GO terms across cancer lineages are Cytosolic transport, Negative regulation of autophagosome maturation, and Endosomal transport. Each is linked with PCYT1A in more than 13 cancer types. Because this analysis shows association rather than direction, both PCYT1A-to-partner and partner-to-PCYT1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by PCYT1A-low versus PCYT1A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYT1A→partner) and Y-score (partner→PCYT1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cytosolic transport →	+0.057	+0.826	<.001	<.001	3	14
OVARY	Negative regulation of autophagosome maturation →	+0.119	+0.663	<.001	.002	3	13
CNS	Endosomal transport →	+0.048	+0.901	<.001	<.001	3	12
STOMACH	Endosomal vesicle fusion →	+0.108	+0.942	.001	<.001	3	12
OESOPHAGUS	Negative regulation of DNA-templated transcription initiation →	+0.100	+0.795	<.001	.005	3	12
OESOPHAGUS	Negative regulation of transcription initiation by RNA polymerase II →	+0.100	+0.795	<.001	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,477 associations by consensus.

Cytosolic transport by PCYT1A expression — SOFT_TISSUE

Explore this box plot interactively →