PCYOX1L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PCYOX1L protein abundance is significantly associated with the RNA expression of many other genes, with 6,250 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCYOX1L-associated genes across cancer lineages are TLE6, SYDE1, and DNAJC27. Each is linked with PCYOX1L in more than 2 cancer types. Because this analysis shows association rather than direction, both PCYOX1L-to-partner and partner-to-PCYOX1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCYOX1L versus TLE6 in BRCA, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYOX1L→partner) and Y-score (partner→PCYOX1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATLE6 →+0.797+0.362.002.00133
OVSYDE1 →+0.650+0.310.005.00733
OVDNAJC27 →+0.351+0.322.007.00133
BRCAKDM4B →+1.053+0.348<.001<.00133
OVSYT11 →+1.558+0.458<.001<.00133
OVAPH1B →+0.821+0.305<.001.00433
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,250 associations by consensus.

PCYOX1L vs TLE6 — BRCA

Per-sample scatter of PCYOX1L vs TLE6 in BRCA (Pearson r = 0.28).

Explore this scatter interactively →

Exploration