PCYOX1L

Across TCGA patient cohorts, PCYOX1L mutation is significantly associated with the RNA expression of many other genes, with 905 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCYOX1L-associated genes across cancer lineages are RNA5SP73, DDX23, and FXNP2. Each is linked with PCYOX1L in more than 2 cancer types. Because this analysis shows association rather than direction, both PCYOX1L-to-partner and partner-to-PCYOX1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP73 grouped by PCYOX1L-low versus PCYOX1L-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCYOX1L→partner) and Y-score (partner→PCYOX1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP73 →	+0.257	+4.516	<.001	.004	3	3
UCEC	DDX23 →	+0.461	+2.906	<.001	.001	3	2
UCEC	FXNP2 →	+0.147	+1.984	.004	.001	3	2
CESC	LINC02438 →	+0.905	+3.989	<.001	.001	3	2
CESC	MIR3197 →	+1.282	+3.910	<.001	.002	3	2
UCEC	SLC25A18 →	+0.306	+1.869	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 905 associations by consensus.

RNA5SP73 by PCYOX1L expression — CESC

Explore this box plot interactively →