PCSK1N

Across TCGA patient cohorts, PCSK1N RNA expression is significantly associated with the protein abundance of many other proteins, with 10,559 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PCSK1N-associated proteins across cancer lineages are VCAN, DNAJC1, and MAP1B. Each is linked with PCSK1N in more than 3 cancer types. Because this analysis shows association rather than direction, both PCSK1N-to-partner and partner-to-PCSK1N results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCSK1N versus VCAN in COAD, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCSK1N→partner) and Y-score (partner→PCSK1N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VCAN →	+0.800	+0.995	<.001	<.001	3	4
LSCC	DNAJC1 →	-0.391	-0.800	<.001	<.001	3	4
COAD	MAP1B →	+0.474	+0.822	<.001	<.001	3	4
LSCC	MAP1B_S1208 →	+0.611	+0.776	.003	.001	3	4
OV	MAP1B_S2271 →	+0.813	+1.281	.001	.005	3	4
LUAD	KIF1A_S937 →	+2.447	+2.423	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,559 associations by consensus.

PCSK1N vs VCAN — COAD

Explore this scatter interactively →