Across TCGA patient cohorts, PCOTH RNA expression is significantly associated with the go_rna of many other GO terms, with 7,086 significant associations in total. THCA shows the largest number of these associations.

The most reproducible PCOTH-associated GO terms across cancer lineages are Intraciliary anterograde transport, Inner mitochondrial membrane organization, and Cristae formation. Each is linked with PCOTH in more than 14 cancer types. Because this analysis shows association rather than direction, both PCOTH-to-partner and partner-to-PCOTH results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCOTH→partner) and Y-score (partner→PCOTH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Intraciliary anterograde transport →	+0.043	+0.323	<.001	.001	2	15
TGCT	Inner mitochondrial membrane organization →	+0.041	+0.365	<.001	<.001	3	12
ACC	Cristae formation →	+0.042	+0.242	.003	.009	1	14
TGCT	Cytochrome complex assembly →	+0.034	+0.319	<.001	<.001	3	11
THYM	Neural tube patterning →	+0.029	+0.592	<.001	<.001	3	11
KICH	L-leucine catabolic process →	+0.066	+0.592	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,086 associations by consensus.

Exploration

PCOTH survival (RNA) · tumor vs normal (RNA) · all PCOTH data types