Across TCGA pan-cancer cohorts, PCOTH RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PCOTH data layer.
The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PCOTH RNA is associated with better overall survival. In most high-consensus cancer types, elevated PCOTH expression acts as an unfavorable survival marker, although some lineages such as STAD and KIRP show a favorable association.
STAD, LGG, and KIRP are the cancer types where PCOTH RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.