PCNP

Across TCGA patient cohorts, PCNP mutation is significantly associated with the RNA expression of many other genes, with 2,414 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCNP-associated genes across cancer lineages are RNVU1-28, RNA5SP413, and ABALON. Each is linked with PCNP in more than 2 cancer types. Because this analysis shows association rather than direction, both PCNP-to-partner and partner-to-PCNP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNVU1-28 grouped by PCNP-low versus PCNP-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCNP→partner) and Y-score (partner→PCNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNVU1-28 →	+0.354	+4.705	.001	.003	3	3
UCEC	RNA5SP413 →	+1.030	+1.987	<.001	.002	3	2
UCEC	ABALON →	+0.429	+2.628	.004	.005	3	1
UCEC	SEPSECS-AS1 →	+0.272	+3.354	.007	.005	3	1
CESC	UBTFL2 →	+0.031	+5.569	<.001	.002	3	1
CESC	LINC01072 →	+0.226	+5.345	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,414 associations by consensus.

RNVU1-28 by PCNP expression — CESC

Explore this box plot interactively →