PCK2

Across TCGA patient cohorts, PCK2 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,585 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCK2-associated proteins across cancer lineages are SUCLG2, PCK2_S304, and DHRS4. Each is linked with PCK2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PCK2-to-partner and partner-to-PCK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCK2 versus SUCLG2 in COAD, with a Pearson correlation of 0.44.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCK2→partner) and Y-score (partner→PCK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SUCLG2 →	+0.529	+0.530	<.001	<.001	3	10
COAD	PCK2_S304 →	+0.729	+0.531	<.001	<.001	3	9
GBM	DHRS4 →	+0.509	+0.521	<.001	<.001	3	8
UCEC	CPT2 →	+0.421	+0.369	<.001	<.001	3	8
PDAC	DLST →	+0.327	+0.510	<.001	<.001	3	8
BRCA	SDHA →	+0.272	+0.446	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,585 associations by consensus.

PCK2 vs SUCLG2 — COAD

Explore this scatter interactively →