PCID2

Across TCGA patient cohorts, PCID2 mutation is significantly associated with the RNA expression of many other genes, with 1,337 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCID2-associated genes across cancer lineages are SCGB1D1, RNU6-508P, and RAET1E-AS1. Each is linked with PCID2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCID2-to-partner and partner-to-PCID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1D1 grouped by PCID2-low versus PCID2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCID2→partner) and Y-score (partner→PCID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SCGB1D1 →	+0.143	+3.622	<.001	.005	3	3
UCEC	RNU6-508P →	+0.269	+3.038	<.001	.006	3	2
UCEC	RAET1E-AS1 →	+0.213	+2.457	.007	.001	3	2
UCEC	PSAT1P4 →	+0.158	+2.033	<.001	.001	3	2
UCEC	FDX1P2 →	+0.099	+2.316	.008	.005	3	2
UCEC	NPLP1 →	+0.185	+1.791	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,337 associations by consensus.

SCGB1D1 by PCID2 expression — SKCM

Explore this box plot interactively →