PCID2

Across TCGA patient cohorts, PCID2 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCID2-associated genes across cancer lineages are GATA3, Annexin-1, and ATM. Each is linked with PCID2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCID2-to-partner and partner-to-PCID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA3 grouped by PCID2-low versus PCID2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCID2→partner) and Y-score (partner→PCID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GATA3 →	+0.168	+3.020	.041	.019	3	2
UCEC	Annexin-1 →	+0.502	+2.189	.029	.034	3	2
UCEC	ATM →	-0.699	-3.446	<.001	.005	3	2
UCEC	14-3-3_beta →	-0.120	-3.143	.006	.018	3	1
UCEC	ERK2 →	+0.248	+2.459	.003	.018	3	1
UCEC	GAPDH →	+0.529	+3.321	.024	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

GATA3 by PCID2 expression — UCEC

Explore this box plot interactively →