PCID2

Across TCGA cell cohorts, PCID2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCID2-associated genes across cancer lineages are SH3GL2, CLPSL1, and KRTAP10-2. Each is linked with PCID2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCID2-to-partner and partner-to-PCID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SH3GL2 grouped by PCID2-low versus PCID2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCID2→partner) and Y-score (partner→PCID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SH3GL2 →	+1.846	+3.474	<.001	.003	3	1
LARGE_INTESTINE	CLPSL1 →	+0.098	+2.791	.001	.005	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.047	+3.257	<.001	.001	3	1
LARGE_INTESTINE	MYMX →	+0.350	+2.841	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SH3GL2 by PCID2 expression — LARGE_INTESTINE

Explore this box plot interactively →