PCGF2

Across TCGA patient cohorts, PCGF2 mutation is significantly associated with the RNA expression of many other genes, with 3,941 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCGF2-associated genes across cancer lineages are PINCR, LINC01932, and TP53TG3. Each is linked with PCGF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCGF2-to-partner and partner-to-PCGF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PINCR grouped by PCGF2-low versus PCGF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCGF2→partner) and Y-score (partner→PCGF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PINCR →	+0.348	+2.185	<.001	<.001	3	2
UCEC	LINC01932 →	+0.346	+2.088	<.001	<.001	3	2
BLCA	TP53TG3 →	+0.048	+5.411	<.001	.005	3	1
BLCA	RNU6-799P →	+0.504	+4.973	<.001	.009	3	1
BLCA	RNU6-902P →	+0.575	+5.177	<.001	.007	3	1
BLCA	PDE2A-AS1 →	+0.121	+4.973	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,941 associations by consensus.

PINCR by PCGF2 expression — UCEC

Explore this box plot interactively →