PCED1B-AS1

Across TCGA pan-cancer cohorts, PCED1B-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated PCED1B-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PCED1B-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PCED1B-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, SKCM, and CESC are the cancer types where PCED1B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.389	0.218	<.001	127	view →
SKCM	OS	Median	All	0.460	0.250	<.001	114	view →
CESC	DFS	Median	All	0.822	0.651	<.001	64	view →
LUAD	DFS	Median	All	0.841	0.740	<.001	52	view →
UCEC	DFS	Quartile	All	0.711	0.529	.002	50	view →
LGG	OS	Median	All	0.365	0.528	<.001	47	view →
BRCA	OS	Median	II,III,IV	0.650	0.492	<.001	30	view →
KIRC	DFS	Quartile	IV	0.232	0.531	.006	26	view →
LIHC	DFS	Tertile	All	0.678	0.525	.016	19	view →
GBM	DFS	Median	All	0.161	0.244	.011	15	view →
CHOL	DFS	Median	All	0.594	0.213	.004	12	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

PCED1B-AS1–HNSC (DFS)

Open the HNSC breakdown →