PCED1B-AS1

Across TCGA pan-cancer cohorts, PCED1B-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of PCED1B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PCED1B-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PCED1B-AS1 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

KIRC, KIRP, and LUSC are the cancer types where PCED1B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PCED1B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+2.132	<.001	12	view →
KIRP	Male	All	+1.254	<.001	9	view →
LUSC	Male	II,III,IV	−1.449	<.001	8	view →
COAD	All	All	−0.476	.003	7	view →
LUAD	All	II,III,IV	−0.460	.001	7	view →
STAD	Female	All	+1.319	.021	4	view →
HNSC	Female	II,III,IV	+0.733	.009	3	view →
LIHC	Female	II,III,IV	+0.635	.012	3	view →
PAAD	All	All	−2.022	.035	2	view →
THCA	Male	IV	+1.283	.004	2	view →
UCEC	All	All	−0.373	.048	2	view →
CHOL	All	All	+1.012	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

PCED1B-AS1–KIRC

Open the KIRC breakdown →