PCED1A

Across TCGA cell cohorts, PCED1A mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCED1A-associated genes across cancer lineages are TCEAL6, TCF21, and SLITRK3. Each is linked with PCED1A in more than 1 cancer types. Because this analysis shows association rather than direction, both PCED1A-to-partner and partner-to-PCED1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCEAL6 grouped by PCED1A-low versus PCED1A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCED1A→partner) and Y-score (partner→PCED1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TCEAL6 →	+0.082	+4.467	<.001	.004	3	1
BLOOD_Leukemia	TCF21 →	+0.008	+3.705	.002	.007	3	1
BLOOD_Leukemia	SLITRK3 →	+0.035	+3.874	<.001	.005	3	1
BLOOD_Leukemia	CALHM4 →	+0.032	+4.269	<.001	.002	3	1
BLOOD_Leukemia	DIRAS2 →	+0.122	+4.087	<.001	.009	3	1
BLOOD_Leukemia	TBPL2 →	+0.132	+4.044	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

TCEAL6 by PCED1A expression — LARGE_INTESTINE

Explore this box plot interactively →