PCDHGC5

Across TCGA patient cohorts, PCDHGC5 mutation is significantly associated with the RNA expression of many other genes, with 1,598 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHGC5-associated genes across cancer lineages are RNA5SP502, HMGB1P50, and MIR6796. Each is linked with PCDHGC5 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDHGC5-to-partner and partner-to-PCDHGC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP502 grouped by PCDHGC5-low versus PCDHGC5-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGC5→partner) and Y-score (partner→PCDHGC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNA5SP502 →	+0.347	+6.149	<.001	.002	3	3
READ	HMGB1P50 →	+0.222	+6.257	<.001	.001	3	2
LIHC	MIR6796 →	+0.748	+5.268	<.001	.006	3	2
HNSC	MIR526A1 →	+0.405	+4.505	<.001	.009	3	2
READ	RNU4ATAC15P →	+0.520	+5.219	<.001	.006	3	2
CESC	RNU7-14P →	+0.759	+4.760	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,598 associations by consensus.

RNA5SP502 by PCDHGC5 expression — LIHC

Explore this box plot interactively →