PCDHGC3

Across TCGA patient cohorts, PCDHGC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,565 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCDHGC3-associated proteins across cancer lineages are TIMP2, KANK2, and LRP1. Each is linked with PCDHGC3 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHGC3-to-partner and partner-to-PCDHGC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGC3 versus TIMP2 in UCEC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGC3→partner) and Y-score (partner→PCDHGC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMP2 →	+0.549	+0.737	.001	<.001	3	5
BRCA	KANK2 →	+0.529	+0.951	<.001	<.001	3	5
BRCA	LRP1 →	+0.514	+1.016	<.001	<.001	3	5
GBM	MCC →	+0.471	+1.341	<.001	<.001	3	5
BRCA	FERMT2 →	+0.486	+0.914	<.001	<.001	3	5
BRCA	SEPTIN11 →	+0.345	+0.720	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,565 associations by consensus.

PCDHGC3 vs TIMP2 — UCEC

Explore this scatter interactively →