PCDHGB7

Across TCGA pan-cancer cohorts, PCDHGB7 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PCDHGB7 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PCDHGB7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PCDHGB7 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

HNSC, LUAD, and GBM are the cancer types where PCDHGB7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	III,IV	0.922	0.428	.008	10	view →
LUAD	DFS	Median	All	0.162	0.888	.014	6	view →
GBM	OS	Median	All	0.476	0.276	.030	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PCDHGB7–HNSC (DFS)

Open the HNSC breakdown →