PCDHGB4

Across TCGA patient cohorts, PCDHGB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,932 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible PCDHGB4-associated GO terms across cancer lineages are Negative regulation of telomere capping, Positive regulation of autophagosome assembly, and Positive regulation of Wnt signaling pathway. Each is linked with PCDHGB4 in more than 22 cancer types. Because this analysis shows association rather than direction, both PCDHGB4-to-partner and partner-to-PCDHGB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere capping grouped by PCDHGB4-low versus PCDHGB4-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB4→partner) and Y-score (partner→PCDHGB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Negative regulation of telomere capping →	+0.057	+1.113	<.001	<.001	3	22
THYM	Positive regulation of autophagosome assembly →	+0.071	+1.225	<.001	<.001	3	21
UCS	Positive regulation of Wnt signaling pathway →	+0.052	+0.612	<.001	.006	1	23
THYM	Androgen receptor signaling pathway →	+0.065	+1.137	<.001	<.001	3	21
THYM	Protein localization to phagophore assembly site →	+0.059	+1.329	<.001	<.001	3	21
DLBC	Regulation of translation in response to endoplasmic reticulum stress →	+0.063	+0.211	<.001	.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,932 associations by consensus.

Negative regulation of telomere capping by PCDHGB4 expression — THYM

Explore this box plot interactively →