PCDHGB2

Across TCGA patient cohorts, PCDHGB2 protein abundance is significantly associated with the RNA expression of many other genes, with 191 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDHGB2-associated genes across cancer lineages are TUBB1, ARHGEF10, and HDAC5. Each is linked with PCDHGB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGB2-to-partner and partner-to-PCDHGB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGB2 versus TUBB1 in GBM, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB2→partner) and Y-score (partner→PCDHGB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TUBB1 →	+0.334	+0.382	.004	.009	3	1
GBM	ARHGEF10 →	+0.370	+0.540	.002	.001	3	1
GBM	HDAC5 →	-0.410	-0.519	<.001	<.001	3	1
GBM	ING4 →	-0.374	-0.627	<.001	<.001	3	1
GBM	NEDD9 →	+0.595	+0.430	<.001	.004	3	1
GBM	TULP1 →	+0.358	+0.488	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 191 associations by consensus.

PCDHGB2 vs TUBB1 — GBM

Explore this scatter interactively →