PCDHGB1

Across TCGA patient cohorts, PCDHGB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,021 significant associations in total. THYM shows the largest number of these associations.

The most reproducible PCDHGB1-associated GO terms across cancer lineages are Insulin-like growth factor receptor signaling pathway, Histone mRNA metabolic process, and Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules. Each is linked with PCDHGB1 in more than 25 cancer types. Because this analysis shows association rather than direction, both PCDHGB1-to-partner and partner-to-PCDHGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Insulin-like growth factor receptor signaling pathway grouped by PCDHGB1-low versus PCDHGB1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB1→partner) and Y-score (partner→PCDHGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Insulin-like growth factor receptor signaling pathway →	+0.066	+0.482	<.001	<.001	3	26
TGCT	Histone mRNA metabolic process →	+0.056	+0.150	<.001	<.001	3	25
OV	Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules →	+0.044	+0.734	<.001	<.001	3	24
TGCT	Embryonic appendage morphogenesis →	+0.070	+0.246	<.001	.003	3	24
DLBC	Negative regulation of telomere capping →	+0.065	+0.260	.003	.003	1	26
THYM	Obsolete selective autophagy →	+0.057	+0.799	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,021 associations by consensus.

Insulin-like growth factor receptor signaling pathway by PCDHGB1 expression — THYM

Explore this box plot interactively →