PCDHGB1

Across TCGA patient cohorts, PCDHGB1 protein abundance is significantly associated with the RNA expression of many other genes, with 170 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDHGB1-associated genes across cancer lineages are PITX3, CLU, and DEPDC7. Each is linked with PCDHGB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGB1-to-partner and partner-to-PCDHGB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGB1 versus PITX3 in GBM, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB1→partner) and Y-score (partner→PCDHGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PITX3 →	+0.202	+0.847	.008	.001	3	1
GBM	CLU →	-0.892	-0.785	.005	.003	3	1
GBM	DEPDC7 →	+0.482	+0.665	.003	.001	3	1
GBM	GALR3 →	+0.436	+0.842	.007	.002	3	1
GBM	SLC9A5 →	+0.514	+0.841	.001	<.001	3	1
GBM	TMBIM6 →	-0.501	-0.940	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 170 associations by consensus.

PCDHGB1 vs PITX3 — GBM

Explore this scatter interactively →