PCDHGA7

Across TCGA cell cohorts, PCDHGA7 mutation is significantly associated with the RNA expression of many other genes, with 1,175 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHGA7-associated genes across cancer lineages are GPR101, MAGEB4, and NUP210L. Each is linked with PCDHGA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGA7-to-partner and partner-to-PCDHGA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR101 grouped by PCDHGA7-low versus PCDHGA7-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA7→partner) and Y-score (partner→PCDHGA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GPR101 →	+0.070	+4.906	<.001	.006	3	2
LARGE_INTESTINE	MAGEB4 →	+0.006	+2.415	.004	.009	3	2
BLOOD_Leukemia	NUP210L →	+0.030	+4.169	.006	<.001	3	2
BLOOD_Leukemia	GPRIN2 →	+0.032	+4.267	<.001	<.001	3	2
BLOOD_Leukemia	USP17L1 →	+0.071	+2.870	<.001	.005	3	2
LARGE_INTESTINE	PICK1 →	+0.566	+3.169	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,175 associations by consensus.

GPR101 by PCDHGA7 expression — OESOPHAGUS

Explore this box plot interactively →