PCDHGA7

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PCDHGA7 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PCDHGA7 data layer compared with 9 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PCDHGA7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PCDHGA7 expression acts as an unfavorable survival marker, although some lineages such as MESO and LIHC show a favorable association.

BLCA, CESC, and LUSC are the cancer types where PCDHGA7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSTertileAll0.1680.726<.00188view →
CESCDFSTertileAll0.7560.889.00154view →
LUSCOSQuartileIII,IV0.5270.862<.00148view →
MESOOSMedianAll0.7190.302.00327view →
STADOSMedianAll0.5190.646.00326view →
BRCADFSTertileII,III,IV0.3430.578.00524view →
LIHCOSTertileIII,IV0.6330.171<.00114view →
KIRPDFSTertileAll0.9560.640.02210view →
CHOLDFSMedianIII,IV0.1270.647.0069view →
DLBCDFSMedianAll1.0000.649.0248view →
KIRCDFSTertileIV0.6990.443.0218view →
LAMLDFSQuartileAll0.6610.291.0196view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PCDHGA7–BLCA (OS)

Kaplan–Meier survival curve for PCDHGA7 RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration