PCDHGA5

Across TCGA patient cohorts, PCDHGA5 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,748 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCDHGA5-associated proteins across cancer lineages are ANXA2, SYNPO2_S729, and TES_S168. Each is linked with PCDHGA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDHGA5-to-partner and partner-to-PCDHGA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGA5 versus ANXA2 in PDAC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA5→partner) and Y-score (partner→PCDHGA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ANXA2 →	+0.383	+0.759	<.001	<.001	3	3
UCEC	SYNPO2_S729 →	+0.705	+0.716	<.001	.002	3	3
BRCA	TES_S168 →	+0.792	+0.586	.001	.001	3	3
PDAC	VIM_S83 →	+0.986	+0.642	.004	<.001	3	3
LSCC	YWHAG →	+0.173	+0.452	.002	.001	3	3
BRCA	OGN →	+1.089	+0.618	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,748 associations by consensus.

PCDHGA5 vs ANXA2 — PDAC

Explore this scatter interactively →