PCDHGA10

Across TCGA patient cohorts, PCDHGA10 protein abundance is significantly associated with the RNA expression of many other genes, with 322 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDHGA10-associated genes across cancer lineages are TXN2, NCF4, and TNFSF13B. Each is linked with PCDHGA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGA10-to-partner and partner-to-PCDHGA10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGA10 versus TXN2 in GBM, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA10→partner) and Y-score (partner→PCDHGA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TXN2 →	-0.298	-0.579	.002	.001	3	1
GBM	NCF4 →	+0.853	+0.510	.001	.001	3	1
GBM	TNFSF13B →	+0.707	+0.842	<.001	<.001	3	1
GBM	MEFV →	+0.678	+0.535	<.001	.005	3	1
GBM	AHR →	+0.790	+0.689	.008	.004	3	1
GBM	CXCL12 →	+1.370	+0.671	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 322 associations by consensus.

PCDHGA10 vs TXN2 — GBM

Explore this scatter interactively →