PCDHGA10

Across TCGA cell cohorts, PCDHGA10 mutation is significantly associated with the mutation status of many other genes, with 3,650 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHGA10-associated genes across cancer lineages are COL7A1, MYH7B, and TDRD6. Each is linked with PCDHGA10 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHGA10-to-partner and partner-to-PCDHGA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL7A1 grouped by PCDHGA10-low versus PCDHGA10-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA10→partner) and Y-score (partner→PCDHGA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	COL7A1 →	+2.588	+3.206	.001	.001	1	5
STOMACH	MYH7B →	+4.807	+4.807	.008	.008	1	5
LUNG_NSCLC_LUAD	TDRD6 →	+3.266	+2.981	.009	.009	1	5
OVARY	FBN2 →	+3.240	+4.467	.004	.004	1	5
OVARY	NCOR1 →	+2.977	+4.273	.006	.006	1	5
OVARY	LAMA3 →	+2.977	+4.273	.006	.006	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,650 associations by consensus.

COL7A1 by PCDHGA10 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →