PCDHB5

Across TCGA patient cohorts, PCDHB5 protein abundance is significantly associated with the RNA expression of many other genes, with 8,446 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCDHB5-associated genes across cancer lineages are MST1P2, MST1L, and DMC1. Each is linked with PCDHB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB5-to-partner and partner-to-PCDHB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHB5 versus MST1P2 in LUAD, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB5→partner) and Y-score (partner→PCDHB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MST1P2 →	-1.706	-0.725	.006	.001	3	2
LUAD	MST1L →	-2.924	-0.583	.003	.007	3	2
GBM	DMC1 →	-0.196	-0.491	.006	.002	3	1
GBM	GSDME →	-0.411	-0.468	.006	.004	3	1
GBM	TXNDC15 →	-0.303	-0.464	.003	.004	3	1
GBM	FAHD2A →	-0.179	-0.373	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,446 associations by consensus.

PCDHB5 vs MST1P2 — LUAD

Explore this scatter interactively →