Across TCGA patient cohorts, PCDHB11 mutation is significantly associated with the RNA expression of many other genes, with 5,738 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHB11-associated genes across cancer lineages are RAD51, HSPA9, and MRPL37. Each is linked with PCDHB11 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHB11-to-partner and partner-to-PCDHB11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB11→partner) and Y-score (partner→PCDHB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51 →	+0.876	+3.534	<.001	<.001	3	5
UCEC	HSPA9 →	+0.513	+1.836	<.001	<.001	3	5
UCEC	MRPL37 →	+0.482	+2.000	<.001	<.001	3	5
UCEC	MRRF →	+0.434	+1.509	<.001	<.001	3	5
STAD	RPF1 →	+0.389	+3.207	.003	.009	3	4
UCEC	NDUFA6 →	+0.542	+1.836	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,738 associations by consensus.

Exploration

PCDHB11 survival (RNA) · tumor vs normal (RNA) · all PCDHB11 data types