PCDHA7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PCDHA7 mutation is significantly associated with the RNA expression of many other genes, with 675 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHA7-associated genes across cancer lineages are DPRX, CTSZ, and IL9R. Each is linked with PCDHA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHA7-to-partner and partner-to-PCDHA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA7→partner) and Y-score (partner→PCDHA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADDPRX →+0.283+5.228<.001.00532
LARGE_INTESTINECTSZ →-1.039-2.459.002.00632
LARGE_INTESTINEIL9R →+0.413+3.447.002.00132
LARGE_INTESTINESERPINE2 →-1.824-3.541.001.00132
LARGE_INTESTINECATSPER3 →+0.420+2.502<.001.00532
LARGE_INTESTINETEDC2 →+0.631+2.502.006.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 675 associations by consensus.

Exploration