PCDHA13

Across TCGA patient cohorts, PCDHA13 mutation is significantly associated with the RNA expression of many other genes, with 5,222 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHA13-associated genes across cancer lineages are TIPIN, XPNPEP1, and TSPY26P. Each is linked with PCDHA13 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHA13-to-partner and partner-to-PCDHA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIPIN grouped by PCDHA13-low versus PCDHA13-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA13→partner) and Y-score (partner→PCDHA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	TIPIN →	+0.554	+3.242	.002	.006	3	5
STAD	XPNPEP1 →	+0.529	+3.716	<.001	<.001	3	5
STAD	TSPY26P →	-0.805	-2.662	<.001	<.001	3	5
SKCM	GBGT1 →	-0.605	-3.309	<.001	<.001	3	5
STAD	PPIP5K1 →	+0.324	+2.541	.005	.008	3	5
STAD	TTC9B →	+0.187	+2.371	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,222 associations by consensus.

TIPIN by PCDHA13 expression — READ

Explore this box plot interactively →