PCDHA12

Across TCGA patient cohorts, PCDHA12 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,990 significant associations in total. THCA shows the largest number of these associations.

The most reproducible PCDHA12-associated GO terms across cancer lineages are Autophagy of mitochondrion, Obsolete selective autophagy, and Autophagosome maturation. Each is linked with PCDHA12 in more than 26 cancer types. Because this analysis shows association rather than direction, both PCDHA12-to-partner and partner-to-PCDHA12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagy of mitochondrion grouped by PCDHA12-low versus PCDHA12-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA12→partner) and Y-score (partner→PCDHA12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Autophagy of mitochondrion →	+0.062	+0.881	.001	<.001	3	26
STAD	Obsolete selective autophagy →	+0.054	+0.374	<.001	<.001	2	27
SCLC	Autophagosome maturation →	+0.090	+1.286	<.001	<.001	2	26
SCLC	Regulation of macroautophagy →	+0.065	+0.969	<.001	<.001	3	25
SCLC	Positive regulation of TORC1 signaling →	+0.077	+1.165	<.001	<.001	3	25
UCS	Golgi vesicle transport →	+0.067	+0.781	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,990 associations by consensus.

Autophagy of mitochondrion by PCDHA12 expression — SCLC

Explore this box plot interactively →