PCDH8

Across TCGA patient cohorts, PCDH8 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,096 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible PCDH8-associated GO terms across cancer lineages are Nucleobase-containing compound transport, Protein stabilization, and Positive regulation of double-strand break repair. Each is linked with PCDH8 in more than 16 cancer types. Because this analysis shows association rather than direction, both PCDH8-to-partner and partner-to-PCDH8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleobase-containing compound transport grouped by PCDH8-low versus PCDH8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH8→partner) and Y-score (partner→PCDH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleobase-containing compound transport →	+0.050	+0.250	<.001	<.001	3	16
STAD	Protein stabilization →	+0.043	+0.202	<.001	<.001	3	16
SCLC	Positive regulation of double-strand break repair →	+0.071	+1.611	.002	.002	2	17
STAD	Positive regulation of Arp2/3 complex-mediated actin nucleation →	+0.061	+0.231	<.001	<.001	3	15
UCS	Axon extension →	+0.053	+2.514	<.001	<.001	2	16
ESCA	RNA localization →	+0.058	+0.459	.008	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,096 associations by consensus.

Nucleobase-containing compound transport by PCDH8 expression — STAD

Explore this box plot interactively →