PCDH8

Across TCGA patient cohorts, PCDH8 protein abundance is significantly associated with the RNA expression of many other genes, with 1,939 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDH8-associated genes across cancer lineages are MAP1LC3A, H19, and RBM38. Each is linked with PCDH8 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDH8-to-partner and partner-to-PCDH8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDH8 versus MAP1LC3A in LSCC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH8→partner) and Y-score (partner→PCDH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP1LC3A →	-1.030	-1.338	.001	.002	3	1
LSCC	H19 →	-2.849	-1.359	<.001	<.001	3	1
LSCC	RBM38 →	-1.026	-1.292	<.001	.003	3	1
LSCC	CCNA1 →	+1.776	+1.538	.003	.007	3	1
LSCC	TEC →	+0.719	+1.107	.002	.007	3	1
LSCC	CREB5 →	+1.052	+1.509	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,939 associations by consensus.

PCDH8 vs MAP1LC3A — LSCC

Explore this scatter interactively →