PCDH19

Across TCGA patient cohorts, PCDH19 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,347 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PCDH19-associated proteins across cancer lineages are FMNL1_S184, STK10, and TNFAIP8. Each is linked with PCDH19 in more than 6 cancer types. Because this analysis shows association rather than direction, both PCDH19-to-partner and partner-to-PCDH19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDH19 versus FMNL1_S184 in LSCC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH19→partner) and Y-score (partner→PCDH19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FMNL1_S184 →	-0.767	-1.605	<.001	<.001	3	7
GBM	STK10 →	-0.404	-0.917	<.001	<.001	3	6
GBM	TNFAIP8 →	-0.752	-1.044	<.001	<.001	3	6
GBM	MYO1F_S1023 →	-0.733	-1.080	<.001	<.001	3	6
HNSC	CASP10 →	-0.388	-0.909	<.001	<.001	3	6
GBM	CASP4 →	-0.574	-0.968	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,347 associations by consensus.

PCDH19 vs FMNL1_S184 — LSCC

Explore this scatter interactively →