PCDH19

Across TCGA patient cohorts, PCDH19 protein abundance is significantly associated with the RNA expression of many other genes, with 5,783 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDH19-associated genes across cancer lineages are FMO6P, MRAP2, and TET1. Each is linked with PCDH19 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDH19-to-partner and partner-to-PCDH19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDH19 versus FMO6P in UCEC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH19→partner) and Y-score (partner→PCDH19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FMO6P →	+1.020	+0.667	.002	.002	3	3
LSCC	MRAP2 →	+1.676	+0.869	<.001	<.001	3	3
UCEC	TET1 →	+0.694	+1.006	<.001	<.001	3	3
LSCC	FRAS1 →	+0.990	+0.940	<.001	<.001	3	3
OV	GNAZ →	+0.923	+0.549	.001	.008	3	2
UCEC	GLCE →	+0.947	+1.042	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,783 associations by consensus.

PCDH19 vs FMO6P — UCEC

Explore this scatter interactively →