PCDH17

Across TCGA cell cohorts, PCDH17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,025 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PCDH17-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Positive regulation of potassium ion transmembrane transport, and Positive regulation of DNA metabolic process. Each is linked with PCDH17 in more than 7 cancer types. Because this analysis shows association rather than direction, both PCDH17-to-partner and partner-to-PCDH17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase II promoter grouped by PCDH17-low versus PCDH17-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH17→partner) and Y-score (partner→PCDH17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription initiation at RNA polymerase II promoter →	+0.087	+2.944	<.001	<.001	3	8
BONE	Positive regulation of potassium ion transmembrane transport →	-0.141	-2.803	<.001	<.001	3	7
BONE	Positive regulation of DNA metabolic process →	+0.112	+3.241	<.001	<.001	3	7
BONE	Protein-DNA complex assembly →	+0.061	+2.277	<.001	<.001	3	7
BONE	Protein-DNA complex organization →	+0.070	+2.277	<.001	<.001	3	7
BONE	Regulation of potassium ion transmembrane transport →	-0.120	-2.619	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,025 associations by consensus.

Transcription initiation at RNA polymerase II promoter by PCDH17 expression — BONE

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