PCDH15

Across TCGA cell cohorts, PCDH15 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,257 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PCDH15-associated GO terms across cancer lineages are mRNA transport, Protein localization to cytoplasmic stress granule, and Visual perception. Each is linked with PCDH15 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDH15-to-partner and partner-to-PCDH15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA transport grouped by PCDH15-low versus PCDH15-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH15→partner) and Y-score (partner→PCDH15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	mRNA transport →	+0.073	+0.146	.002	.006	3	5
SOFT_TISSUE	Protein localization to cytoplasmic stress granule →	+0.087	+0.872	<.001	.001	3	5
UPPER_AERODIGESTIVE_TRACT	Visual perception →	-0.065	-0.202	<.001	<.001	3	4
STOMACH	Action potential →	-0.111	-0.140	<.001	.009	3	4
BLOOD_Lymphoma	Positive regulation of collagen fibril organization →	-0.140	-0.835	<.001	.004	3	4
LUNG_NSCLC_LUAD	Tetrapyrrole metabolic process →	+0.055	+0.205	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,257 associations by consensus.

mRNA transport by PCDH15 expression — STOMACH

Explore this box plot interactively →