PCDH11X

Across TCGA cell cohorts, PCDH11X RNA expression is significantly associated with the go_rna of many other GO terms, with 1,950 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PCDH11X-associated GO terms across cancer lineages are Endocardial cushion fusion, Positive regulation of endothelial cell migration, and Regulation of cell junction assembly. Each is linked with PCDH11X in more than 3 cancer types. Because this analysis shows association rather than direction, both PCDH11X-to-partner and partner-to-PCDH11X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endocardial cushion fusion grouped by PCDH11X-low versus PCDH11X-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH11X→partner) and Y-score (partner→PCDH11X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Endocardial cushion fusion →	-1.322	-1.270	<.001	<.001	3	4
BONE	Positive regulation of endothelial cell migration →	-0.110	-1.771	<.001	<.001	3	4
BONE	Regulation of cell junction assembly →	-0.060	-1.131	<.001	.007	3	4
BONE	Regulation of isotype switching to IgE isotypes →	-1.161	-1.933	<.001	<.001	3	4
BONE	Positive regulation of isotype switching to IgE isotypes →	-1.161	-1.933	<.001	<.001	3	4
BONE	Atrial cardiac muscle cell differentiation →	-1.202	-1.515	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,950 associations by consensus.

Endocardial cushion fusion by PCDH11X expression — LUNG_SCLC

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