PCCA

Across TCGA patient cohorts, PCCA RNA expression is significantly associated with the protein abundance of many other proteins, with 13,777 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PCCA-associated proteins across cancer lineages are NAXD, PCCB, and FARP1. Each is linked with PCCA in more than 6 cancer types. Because this analysis shows association rather than direction, both PCCA-to-partner and partner-to-PCCA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCCA versus NAXD in BRCA, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCCA→partner) and Y-score (partner→PCCA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NAXD →	+0.452	+0.629	<.001	<.001	3	7
OV	PCCB →	+0.669	+0.903	<.001	<.001	3	7
BRCA	FARP1 →	+0.383	+0.452	<.001	<.001	3	6
HNSC	EIF2AK2 →	-0.307	-0.535	.005	.004	3	5
GBM	DOK3 →	-0.510	-0.370	<.001	<.001	3	5
BRCA	ESD →	+0.357	+0.634	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,777 associations by consensus.

PCCA vs NAXD — BRCA

Explore this scatter interactively →